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chemidoc mp imaging system  (Bio-Rad)
99
Bio-Rad chemidoc mp imaging system
Figure 3. Efficacy of JBI-589 in the G-CSF-modified collagen-induce arthritis model in C57BL/6 mice. Vehicle (water) or 50 mg/ kg of JBI-589 was orally administered twice daily from day 20 to day 56. (a) Arthritis incidence (left) and severity and body weight (right) of vehicle- and JBI-589-treated mice (n = 10:10). (b) Serum IL-6 and serum anti-collagen IgG and IgG2c antibody on day 56. (c) The changes in plasma levels of citrullinated histone H3 on day 22. (d) Representative images of micro-CT of ankle joints (left) and quantification of eroded surface of joints (right). (e) Representative images of H&E staining (left) and determination of inflammation in H&E stains by scale of 0 (no inflammation) to 3 (severe inflamed joint) depending on the number of inflammatory cells in the synovial cavity (exudate) and synovial tissue (infiltrate) (right). (*: Proliferated synovial tissue. scale bar = 500 μm) (f) Representative images of Ly6G and H3Cit immunostaining of ankle joints. (JS: Joint space, *: Synovial tissue, scale bar = 100 μm.). Images were obtained using a Zeiss Axiovert 200 M wide-field fluorescence microscope (Zeiss, Oberkochen, Germany) with the Zeiss AxioVision software (Version 4.6.3.0). (g) Western blot of MPO, H4Cit, and GAPDH (left) levels in synovial tissue (n = 5:5) was detected by <t>ChemiDoc</t> MP Imaging System (Bio-Rad Laboratories) and quantification by densitometry (middle and right, relative expression to GAPDH). (h) Representative images of blots with serum anti-native H3 antibody and anti-H3Cit antibody (upper) and quantification by densitometry (lower, anti-H3Cit/anti-native H3). Images were processed with Fiji/ImageJ software61 (National Institutes of Health) for the western blot and the microscopy image analysis.
Chemidoc Mp Imaging System, supplied by Bio-Rad, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/imaging+densitometer+axiovision/ChemiDoc+MP+Imaging+System/pm36823444-106-41-45
Average 99 stars, based on 1 article reviews
chemidoc mp imaging system - by Bioz Stars, 2026-10
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axio observe z1 inverted microscope  (Carl Zeiss)
99
Carl Zeiss axio observe z1 inverted microscope
Figure 3. Efficacy of JBI-589 in the G-CSF-modified collagen-induce arthritis model in C57BL/6 mice. Vehicle (water) or 50 mg/ kg of JBI-589 was orally administered twice daily from day 20 to day 56. (a) Arthritis incidence (left) and severity and body weight (right) of vehicle- and JBI-589-treated mice (n = 10:10). (b) Serum IL-6 and serum anti-collagen IgG and IgG2c antibody on day 56. (c) The changes in plasma levels of citrullinated histone H3 on day 22. (d) Representative images of micro-CT of ankle joints (left) and quantification of eroded surface of joints (right). (e) Representative images of H&E staining (left) and determination of inflammation in H&E stains by scale of 0 (no inflammation) to 3 (severe inflamed joint) depending on the number of inflammatory cells in the synovial cavity (exudate) and synovial tissue (infiltrate) (right). (*: Proliferated synovial tissue. scale bar = 500 μm) (f) Representative images of Ly6G and H3Cit immunostaining of ankle joints. (JS: Joint space, *: Synovial tissue, scale bar = 100 μm.). Images were obtained using a Zeiss Axiovert 200 M wide-field fluorescence microscope (Zeiss, Oberkochen, Germany) with the Zeiss AxioVision software (Version 4.6.3.0). (g) Western blot of MPO, H4Cit, and GAPDH (left) levels in synovial tissue (n = 5:5) was detected by <t>ChemiDoc</t> MP Imaging System (Bio-Rad Laboratories) and quantification by densitometry (middle and right, relative expression to GAPDH). (h) Representative images of blots with serum anti-native H3 antibody and anti-H3Cit antibody (upper) and quantification by densitometry (lower, anti-H3Cit/anti-native H3). Images were processed with Fiji/ImageJ software61 (National Institutes of Health) for the western blot and the microscopy image analysis.
Axio Observe Z1 Inverted Microscope, supplied by Carl Zeiss, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/imaging+densitometer+axiovision/Inverted+microscope+Axio+Observer+3/10__3727_slash_096368915x689550-116-8-13
Average 99 stars, based on 1 article reviews
axio observe z1 inverted microscope - by Bioz Stars, 2026-10
99/100 stars
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Image Search Results


Figure 3. Efficacy of JBI-589 in the G-CSF-modified collagen-induce arthritis model in C57BL/6 mice. Vehicle (water) or 50 mg/ kg of JBI-589 was orally administered twice daily from day 20 to day 56. (a) Arthritis incidence (left) and severity and body weight (right) of vehicle- and JBI-589-treated mice (n = 10:10). (b) Serum IL-6 and serum anti-collagen IgG and IgG2c antibody on day 56. (c) The changes in plasma levels of citrullinated histone H3 on day 22. (d) Representative images of micro-CT of ankle joints (left) and quantification of eroded surface of joints (right). (e) Representative images of H&E staining (left) and determination of inflammation in H&E stains by scale of 0 (no inflammation) to 3 (severe inflamed joint) depending on the number of inflammatory cells in the synovial cavity (exudate) and synovial tissue (infiltrate) (right). (*: Proliferated synovial tissue. scale bar = 500 μm) (f) Representative images of Ly6G and H3Cit immunostaining of ankle joints. (JS: Joint space, *: Synovial tissue, scale bar = 100 μm.). Images were obtained using a Zeiss Axiovert 200 M wide-field fluorescence microscope (Zeiss, Oberkochen, Germany) with the Zeiss AxioVision software (Version 4.6.3.0). (g) Western blot of MPO, H4Cit, and GAPDH (left) levels in synovial tissue (n = 5:5) was detected by ChemiDoc MP Imaging System (Bio-Rad Laboratories) and quantification by densitometry (middle and right, relative expression to GAPDH). (h) Representative images of blots with serum anti-native H3 antibody and anti-H3Cit antibody (upper) and quantification by densitometry (lower, anti-H3Cit/anti-native H3). Images were processed with Fiji/ImageJ software61 (National Institutes of Health) for the western blot and the microscopy image analysis.

Journal: Scientific reports

Article Title: Alleviation of arthritis through prevention of neutrophil extracellular traps by an orally available inhibitor of protein arginine deiminase 4.

doi: 10.1038/s41598-023-30246-2

Figure Lengend Snippet: Figure 3. Efficacy of JBI-589 in the G-CSF-modified collagen-induce arthritis model in C57BL/6 mice. Vehicle (water) or 50 mg/ kg of JBI-589 was orally administered twice daily from day 20 to day 56. (a) Arthritis incidence (left) and severity and body weight (right) of vehicle- and JBI-589-treated mice (n = 10:10). (b) Serum IL-6 and serum anti-collagen IgG and IgG2c antibody on day 56. (c) The changes in plasma levels of citrullinated histone H3 on day 22. (d) Representative images of micro-CT of ankle joints (left) and quantification of eroded surface of joints (right). (e) Representative images of H&E staining (left) and determination of inflammation in H&E stains by scale of 0 (no inflammation) to 3 (severe inflamed joint) depending on the number of inflammatory cells in the synovial cavity (exudate) and synovial tissue (infiltrate) (right). (*: Proliferated synovial tissue. scale bar = 500 μm) (f) Representative images of Ly6G and H3Cit immunostaining of ankle joints. (JS: Joint space, *: Synovial tissue, scale bar = 100 μm.). Images were obtained using a Zeiss Axiovert 200 M wide-field fluorescence microscope (Zeiss, Oberkochen, Germany) with the Zeiss AxioVision software (Version 4.6.3.0). (g) Western blot of MPO, H4Cit, and GAPDH (left) levels in synovial tissue (n = 5:5) was detected by ChemiDoc MP Imaging System (Bio-Rad Laboratories) and quantification by densitometry (middle and right, relative expression to GAPDH). (h) Representative images of blots with serum anti-native H3 antibody and anti-H3Cit antibody (upper) and quantification by densitometry (lower, anti-H3Cit/anti-native H3). Images were processed with Fiji/ImageJ software61 (National Institutes of Health) for the western blot and the microscopy image analysis.

Article Snippet: Images were obtained using a Zeiss Axiovert 200 M wide-field fluorescence microscope (Zeiss, Oberkochen, Germany) with the Zeiss AxioVision software (Version 4.6.3.0). (g) Western blot of MPO, H4Cit, and GAPDH (left) levels in synovial tissue (n = 5:5) was detected by ChemiDoc MP Imaging System (Bio-Rad Laboratories) and quantification by densitometry (middle and right, relative expression to GAPDH). (h) Representative images of blots with serum anti-native H3 antibody and anti-H3Cit antibody (upper) and quantification by densitometry (lower, anti-H3Cit/anti-native H3).

Techniques: Modification, Clinical Proteomics, Micro-CT, Staining, Immunostaining, Fluorescence, Microscopy, Software, Western Blot, Imaging, Expressing